diff --git a/CHANGELOG.md b/CHANGELOG.md
index c8c5bba..8a7cb0c 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -1,10 +1,12 @@
 # Changes
 
 * 2.4.next in progress
+  * Fix `set-options!` (only `:checking` worked in 2.4.947).
   * Fix `:cast` formatting when quoting is enabled, via PR [#443](https://github.com/seancorfield/honeysql/pull/443) [duddlf23](https://github.com/duddlf23).
   * Fix [#441](https://github.com/seancorfield/honeysql/issues/441) by adding `:replace-into` to in-flight clause order (as well as registering it for the `:mysql` dialect).
   * Fix [#434](https://github.com/seancorfield/honeysql/issues/434) by special-casing `:'ARRAY`.
   * Fix [#433](https://github.com/seancorfield/honeysql/issues/433) by supporting additional `WITH` syntax, via PR [#432](https://github.com/seancorfield/honeysql/issues/432), [@MawiraIke](https://github.com/MawiraIke). _[Technically, this was in 2.4.947, but I kept the issue open while I wordsmithed the documentation]_
+  * Address [#405](https://github.com/seancorfield/honeysql/issues/405) by adding `:numbered` option, which can also be set globally using `set-options!`.
 
 * 2.4.947 -- 2022-11-05
   * Fix [#439](https://github.com/seancorfield/honeysql/issues/439) by rewriting how DDL options are processed; also fixes [#386](https://github.com/seancorfield/honeysql/issues/386) and [#437](https://github.com/seancorfield/honeysql/issues/437); **Whilst this is intended to be purely a bug fix, it has the potential to be a breaking change -- hence the version jump to 2.4!**
diff --git a/README.md b/README.md
index edb715d..02f73c1 100644
--- a/README.md
+++ b/README.md
@@ -116,6 +116,13 @@ If you want to format the query as a string with no parameters (e.g. to use the
 => ["SELECT a, b, c FROM foo WHERE foo.a = 'baz'"]
 ```
 
+As seen above, the default parameterization uses positional parameters (`?`) with the order of values in the generated vector matching the order of those placeholders in the SQL. As of 2.4.next, you can specified `:numbered true` as an option to produce numbered parameters (`$1`, `$2`, etc):
+
+```clojure
+(sql/format sqlmap {:numbered true})
+=> ["SELECT a, b, c FROM foo WHERE foo.a = $1" "baz"]
+```
+
 Namespace-qualified keywords (and symbols) are generally treated as table-qualified columns: `:foo/bar` becomes `foo.bar`, except in contexts where that would be illegal (such as the list of columns in an `INSERT` statement). This approach is likely to be more compatible with code that uses libraries like [`next.jdbc`](https://github.com/seancorfield/next-jdbc) and [`seql`](https://github.com/exoscale/seql), as well as being more convenient in a world of namespace-qualified keywords, following the example of `clojure.spec` etc.
 
 ```clojure
@@ -388,6 +395,19 @@ INSERT INTO comp_table
 VALUES (?, (?, ?)), (?, (?, ?))
 "
 "small" 1 "inch" "large" 10 "feet"]
+;; with numbered parameters:
+(-> (insert-into :comp_table)
+    (columns :name :comp_column)
+    (values
+     [["small" (composite 1 "inch")]
+      ["large" (composite 10 "feet")]])
+    (sql/format {:pretty true :numbered true}))
+=> ["
+INSERT INTO comp_table
+(name, comp_column)
+VALUES ($1, ($2, $3)), ($4, ($5, $6))
+"
+"small" 1 "inch" "large" 10 "feet"]
 ;; or as pure data DSL:
 (-> {:insert-into [:comp_table],
      :columns [:name :comp_column],
@@ -608,6 +628,12 @@ Keywords that begin with `?` are interpreted as bindable parameters:
     (where [:= :a :?baz])
     (sql/format {:params {:baz "BAZ"}}))
 => ["SELECT id FROM foo WHERE a = ?" "BAZ"]
+;; or with numbered parameters:
+(-> (select :id)
+    (from :foo)
+    (where [:= :a :?baz])
+    (sql/format {:params {:baz "BAZ"} :numbered true}))
+=> ["SELECT id FROM foo WHERE a = $1" "BAZ"]
 ;; or as pure data DSL:
 (-> {:select [:id], :from [:foo], :where [:= :a :?baz]}
     (sql/format {:params {:baz "BAZ"}}))
@@ -832,6 +858,24 @@ LIMIT ?
 OFFSET ?
 "
 "bort" "gabba" 1 2 2 3 1 2 3 10 20 0 50 10]
+;; with numbered parameters:
+(sql/format big-complicated-map
+            {:params {:param1 "gabba" :param2 2}
+             :pretty true :numbered true})
+=> ["
+SELECT DISTINCT f.*, b.baz, c.quux, b.bla AS \"bla-bla\", NOW(), @x := 10
+FROM foo AS f, baz AS b
+INNER JOIN draq ON f.b = draq.x INNER JOIN eldr ON f.e = eldr.t
+LEFT JOIN clod AS c ON f.a = c.d
+RIGHT JOIN bock ON bock.z = c.e
+WHERE ((f.a = $1) AND (b.baz <> $2)) OR (($3 < $4) AND ($5 < $6)) OR (f.e IN ($7, $8, $9)) OR f.e BETWEEN $10 AND $11
+GROUP BY f.a, c.e
+HAVING $12 < f.e
+ORDER BY b.baz DESC, c.quux ASC, f.a NULLS FIRST
+LIMIT $13
+OFFSET $14
+"
+"bort" "gabba" 1 2 2 3 1 2 3 10 20 0 50 10]
 ```
 ```clojure
 ;; Printable and readable
@@ -882,8 +926,13 @@ Or perhaps your database supports syntax like `a BETWIXT b AND c`, in which case
 ;; example usage:
 (-> (select :a) (where [:betwixt :a 1 10]) sql/format)
 => ["SELECT a WHERE a BETWIXT ? AND ?" 1 10]
+;; with numbered parameters:
+(-> (select :a) (where [:betwixt :a 1 10]) (sql/format {:numbered true}))
+=> ["SELECT a WHERE a BETWIXT $1 AND $2" 1 10]
 ```
 
+> Note: the generation of positional placeholders (`?`) or numbered placeholders (`$1`, `$2`, etc) is handled automatically by `format-expr` so you get this behavior "for free" in your extensions, as long as you use the public API for `honey.sql`. You should avoid writing extensions that generate placeholders directly if you want them to work with numbered parameters.
+
 You can also register SQL clauses, specifying the keyword, the formatting function, and an existing clause that this new clause should be processed before:
 
 ```clojure
@@ -909,6 +958,6 @@ If you find yourself registering an operator, a function (syntax), or a new clau
 
 ## License
 
-Copyright (c) 2020-2021 Sean Corfield. HoneySQL 1.x was copyright (c) 2012-2020 Justin Kramer and Sean Corfield.
+Copyright (c) 2020-2022 Sean Corfield. HoneySQL 1.x was copyright (c) 2012-2020 Justin Kramer and Sean Corfield.
 
 Distributed under the Eclipse Public License, the same as Clojure.
diff --git a/doc/differences-from-1-x.md b/doc/differences-from-1-x.md
index de4044b..5b47979 100644
--- a/doc/differences-from-1-x.md
+++ b/doc/differences-from-1-x.md
@@ -104,7 +104,7 @@ You can now select a non-ANSI dialect of SQL using the new `honey.sql/set-dialec
 
 ## Option Changes
 
-The `:quoting <dialect>` option has superseded by the new dialect machinery and a new `:quoted` option that turns quoting on or off. You either use `:dialect <dialect>` instead or set a default dialect (via `set-dialect!`) and then use `:quoted true` in `format` calls where you want quoting.
+The `:quoting <dialect>` option has been superseded by the new dialect machinery and a new `:quoted` option that turns quoting on or off. You either use `:dialect <dialect>` instead (which turns on quoting by default) or set a default dialect (via `set-dialect!`) and then use `:quoted true` in `format` calls where you want quoting.
 
 SQL entity names are automatically quoted if you specify a `:dialect` option to `format`, unless you also specify `:quoted false`.
 
@@ -112,7 +112,7 @@ The following options are no longer supported:
 * `:allow-dashed-names?` -- if you provide dashed-names in 2.x, they will be left as-is if quoting is enabled, else they will be converted to snake_case (so you will either get `"dashed-names"` with quoting or `dashed_names` without). If you want dashed-names to be converted to snake_case when `:quoted true`, you also need to specify `:quoted-snake true`.
 * `:allow-namespaced-names?` -- this supported `foo/bar` column names in SQL which I'd like to discourage.
 * `:namespace-as-table?` -- this is the default in 2.x: `:foo/bar` will be treated as `foo.bar` which is more in keeping with `next.jdbc`.
-* `:parameterizer` -- this would add a lot of complexity to the formatting engine and I do not know how widely it was used (especially in its arbitrarily extensible form).
+* `:parameterizer` -- this would add a lot of complexity to the formatting engine and I do not know how widely it was used (especially in its arbitrarily extensible form). _[As of 2.4.next, the ability to generated SQL with numbered parameters, i.e., `$1` instead of positional parameters, `?`, has been added via the `:numbered true` option]_
 * `:return-param-names` -- this was added to 1.x back in 2013 without an associated issue or PR so I've no idea what use case this was intended to support.
 
 > Note: I expect some push back on those first three options and the associated behavior changes.
diff --git a/doc/getting-started.md b/doc/getting-started.md
index 1b40eab..3bd928e 100644
--- a/doc/getting-started.md
+++ b/doc/getting-started.md
@@ -110,6 +110,8 @@ Some "functions" are considered to be operators. In general,
 `42` and `"c"` lifted out into the overall vector result
 (with a SQL string followed by all its parameters).
 
+> Note: you can use the `:numbered true` option to `format` to produce SQL containing numbered placeholders, like `FOO(a, $1, $2)`, instead of positional placeholders (`?`).
+
 Operators can be strictly binary or variadic (most are strictly binary).
 Special syntax can have zero or more arguments and each form is
 described in the [Special Syntax](special-syntax.md) section.
@@ -179,7 +181,7 @@ expression requires an extra level of nesting:
 
 As indicated in the preceding sections, values found in the DSL data structure
 that are not keywords or symbols are lifted out as positional parameters.
-They are replaced by `?` in the generated SQL string and added to the
+By default, they are replaced by `?` in the generated SQL string and added to the
 parameter list in order:
 
 <!-- :test-doc-blocks/skip -->
@@ -187,6 +189,14 @@ parameter list in order:
 [:between :size 10 20] ;=> "size BETWEEN ? AND ?" with parameters 10 and 20
 ```
 
+If you specify the `:numbered true` option to `format`, numbered placeholders (`$1`, `$2`, etc) will be used instead of positional placeholders (`?`).
+
+<!-- :test-doc-blocks/skip -->
+```clojure
+;; with :numbered true option:
+[:between :size 10 20] ;=> "size BETWEEN $1 AND $2" with parameters 10 and 20
+```
+
 HoneySQL also supports named parameters. There are two ways
 of identifying a named parameter:
 * a keyword or symbol that begins with `?`
@@ -206,6 +216,18 @@ call as the `:params` key of the options hash map.
 ;;=> ["SELECT * FROM table WHERE a = ?" 42]
 ```
 
+Or with `:numbered true`:
+```clojure
+(sql/format {:select [:*] :from [:table]
+             :where [:= :a :?x]}
+            {:params {:x 42} :numbered true})
+;;=> ["SELECT * FROM table WHERE a = $1" 42]
+(sql/format {:select [:*] :from [:table]
+             :where [:= :a [:param :x]]}
+            {:params {:x 42} :numbered true})
+;;=> ["SELECT * FROM table WHERE a = $1" 42]
+```
+
 ## Functional Helpers
 
 In addition to the hash map (and sequences) approach of building
diff --git a/doc/options.md b/doc/options.md
index e6cb061..739fb2e 100644
--- a/doc/options.md
+++ b/doc/options.md
@@ -19,6 +19,7 @@ All options may be omitted. The default behavior of each option is described in
 * `:checking` -- `:none` (default), `:basic`, or `:strict` to control the amount of lint-like checking that HoneySQL performs,
 * `:dialect` -- a keyword that identifies a dialect to be used for this specific call to `format`; the default is to use what was specified in `set-dialect!` or `:ansi` if no other dialect has been set,
 * `:inline` -- a Boolean indicating whether or not to inline parameter values, rather than use `?` placeholders and a sequence of parameter values; the default is `false` -- values are not inlined,
+* `:numbered` -- a Boolean indicating whether to generate numbered placeholders in the generated SQL (`$1`, `$2`, etc) or positional placeholders (`?`); the default is `false` (positional placeholders); this option was added in 2.4.next,
 * `:params` -- a hash map providing values for named parameters, identified by names (keywords or symbols) that start with `?` in the DSL; the default is that any such named parameters will have `nil` values,
 * `:quoted` -- a Boolean indicating whether or not to quote (strop) SQL entity names (table and column names); the default is `nil` -- alphanumeric SQL entity names are not quoted but (as of 2.3.928) "unusual" SQL entity names are quoted; a `false` value turns off all quoting,
 * `:quoted-snake` -- a Boolean indicating whether or not quoted and string SQL entity names should have `-` replaced by `_`; the default is `false` -- quoted and string SQL entity names are left exactly as-is,
@@ -29,6 +30,7 @@ global defaults of certain options:
 
 * `:checking` -- can be `:basic` or `:strict`; specify `:none` to reset to the default,
 * `:inline` -- can be `true` but consider the security issues this causes by not using parameterized SQL statements; specify `false` (or `nil`) to reset to the default,
+* `:numbered` -- can be `true` or `false`; specify `false` to reset to the default,
 * `:quoted` -- can be `true` or `false`; specify `nil` to reset to the default; calling `set-dialect!` or providing a `:dialect` option to `format` will override the global default,
 * `:quoted-snake` -- can be `true`; specify `false` (or `nil`) to reset to the default.
 
@@ -96,6 +98,13 @@ was wrapped in `[:inline `..`]`:
 
 > Note: you can provide additional inline formatting by extending the `InlineValue` protocol from `honey.sql.protocols` to new types.
 
+## `:numbered`
+
+By default, HoneySQL generates SQL using positional placeholders (`?`).
+Specifying `:numbered true` tells HoneySQL to generate SQL using
+numbered placeholders instead (`$1`, `$2`, etc). This can be set
+globally using `set-options!`.
+
 ## `:params`
 
 The `:params` option provides a mapping from named parameters
diff --git a/doc/postgresql.md b/doc/postgresql.md
index 4721f30..6b9dc71 100644
--- a/doc/postgresql.md
+++ b/doc/postgresql.md
@@ -10,6 +10,12 @@ Everything that the nilenso library provided (in 0.4.112) is implemented
 directly in HoneySQL 2.x although a few things have a
 slightly different syntax.
 
+If you are using HoneySQL with the Node.js PostgreSQL driver, it
+only accepts numbered placeholders, not positional placeholders,
+so you will need to specify the `:numbered true` option that was
+added in 2.4.next. You may find it convenient to set this option
+globally, via `set-options!`.
+
 ## Code Examples
 
 The code examples herein assume:
diff --git a/src/honey/sql.cljc b/src/honey/sql.cljc
index 7a93c7b..134ef7e 100644
--- a/src/honey/sql.cljc
+++ b/src/honey/sql.cljc
@@ -120,6 +120,7 @@
 (def ^:private default-quoted-snake (atom nil))
 (def ^:private default-inline (atom nil))
 (def ^:private default-checking (atom :none))
+(def ^:private default-numbered (atom false))
 
 (def ^:private ^:dynamic *dialect* nil)
 ;; nil would be a better default but that makes testing individual
@@ -1667,7 +1668,10 @@
   ([data opts]
    (let [cache    (:cache opts)
          dialect? (contains? opts :dialect)
-         dialect  (when dialect? (get @dialects (check-dialect (:dialect opts))))]
+         dialect  (when dialect? (get @dialects (check-dialect (:dialect opts))))
+         numbered (if (contains? opts :numbered)
+                    (:numbered opts)
+                    @default-numbered)]
      (binding [*dialect* (if dialect? dialect @default-dialect)
                *caching* cache
                *checking* (if (contains? opts :checking)
@@ -1681,7 +1685,7 @@
                *inline*  (if (contains? opts :inline)
                            (:inline opts)
                            @default-inline)
-               *numbered* (when (:numbered opts)
+               *numbered* (when numbered
                             (atom []))
                *quoted*  (cond (contains? opts :quoted)
                                (:quoted opts)
@@ -1722,11 +1726,12 @@
   "Set default values for any or all of the following options:
   * :checking
   * :inline
+  * :numbered
   * :quoted
   * :quoted-snake
   Note that calling `set-dialect!` can override the default for `:quoted`."
   [opts]
-  (let [unknowns (dissoc opts :checking :inline :quoted :quoted-snake)]
+  (let [unknowns (dissoc opts :checking :inline :numbered :quoted :quoted-snake)]
     (when (seq unknowns)
       (throw (ex-info (str (str/join ", " (keys unknowns))
                            " are not options that can be set globally.")
@@ -1734,11 +1739,13 @@
     (when (contains? opts :checking)
       (reset! default-checking (:checking opts)))
     (when (contains? opts :inline)
-      (reset! default-checking (:inline opts)))
+      (reset! default-inline (:inline opts)))
+    (when (contains? opts :numbered)
+      (reset! default-numbered (:numbered opts)))
     (when (contains? opts :quoted)
-      (reset! default-checking (:quoted opts)))
+      (reset! default-quoted (:quoted opts)))
     (when (contains? opts :quoted-snake)
-      (reset! default-checking (:quoted-snake opts)))))
+      (reset! default-quoted-snake (:quoted-snake opts)))))
 
 (defn clause-order
   "Return the current order that known clauses will be applied when
diff --git a/test/honey/sql/helpers_test.cljc b/test/honey/sql/helpers_test.cljc
index 33ee9bf..be159ba 100644
--- a/test/honey/sql/helpers_test.cljc
+++ b/test/honey/sql/helpers_test.cljc
@@ -1,4 +1,4 @@
-;; copyright (c) 2020-2021 sean corfield, all rights reserved
+;; copyright (c) 2020-2022 sean corfield, all rights reserved
 
 (ns honey.sql.helpers-test
   (:refer-clojure :exclude [filter for group-by partition-by set update])